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Which Dermal Filler Lasts the Longest?

Drugstore skincare products don’t wholly reduce facial wrinkles, lines nor restore the loss of volume, which is why some people use dermal fillers. When thinking of injectable fillers, you’d  want to consider the clinical longevity, its look and feel,  and the common side effects. All of these can help you weigh what’s best for you.

So which dermal filler lasts the longest? Sculptra lasts the longest among other dermal fillers. Most fillers use hyaluronic acid, a naturally-occurring substance that helps in elastin and human collagen production Sculptra, on the other hand, uses poly-L-lactic acid. As a result, it plumps the facial skin and keeps it hydrated. Some of the most commonly known dermal filler products with long-lasting rejuvenation effects are Juvederm, Restylane Lyft, Radiesse, and Sculptra.

The Perfect Filler For The Perfect You

What is your perfect cosmetic filler? Whether in your lips, cheeks, or anywhere else, our providers know exactly how to make you look your best. Call us today to learn more.

Sculptra: Why Does It Last Longer Than Other Dermal Fillers?

Sculptra is an injectable treatment that employs poly-L-lactic acid (PLLA), stimulating collagen production. FDA authorized its usage in 2009 to treat nasolabial folds and deep wrinkles, with notable success compared to other dermal fillers due to its longevity.

Sculptra’s longevity is because, unlike some other types of fillers that apply a natural substance to facial folds or deeper wrinkles beneath the surface, Sculptra encourages skin cell growth. Since collagen is so helpful in increasing facial volume, a filler product that boosts its production enhances the skin and face noticeably.

Other face and lip injections, mainly those hyaluronic acid-based fillers, do not last as long or are not as beneficial because they merely alter the facial feature. Sculptra’s ability to collagen stimulation enables its effects to last longer after the completed initial treatment, with possibly additional procedures based on the patient’s normal routine.

Since that might not be the “better” dermal filler (which can only be ascertained individually), Sculptra surpasses other facial fillers based on the length of its results. Cosmetic surgeons and dermatologists must always suggest Sculptra to prepared patients who want lengthy results.

Sculptra consists of poly-L-lactic acid, which is a biocompatible ingredient  that is gradually and naturally absorbed by the human body. This helps rebuild natural collagen production through additional treatment sessions conducted by a licensed facial plastic surgeon. 

The dermal filler injections go into the deep skin folds, where a collagen stimulator supports the skin’s framework. Sculptra helps promote collagen growth in the body. The number of facial injections and minutes per session differ from patient to patient, based on the lost collagen quantity. On an average treatment, three filler injections visits are necessary over a couple of months. 

Sculptra functions as a collagen stimulator by enhancing the volume of facial folds and wrinkles, gradually training the skin to fill them in over a period. While Sculptra produces less noticeable and instant results than other facial fillers and cosmetic injectables such as Botox, its general effectiveness lies in its longevity.

The effects of Sculptra usually last somewhere between 2 to 5 years on average, based on the injection sites and the person’s lifestyle. A wide variety of common target areas are:

  • Deep smile lines
  • Nasolabial folds 
  • Laugh lines
  • Vertical lines
  • Marionette lines
  • Severe wrinkles on the chest, elbows, and knees

And apart from filling in deeper lines and wrinkles, it can also add weight and definition to specific body parts, acting as a kind of body sculpture. It is not advisable in regions with irregular scarring, skin conditions such as acne, or other skin inflammatory reactions and allergies.

Read More: Bolus Injection vs Serial Puncture Technique for Dermal Fillers

Other Lasting Dermal Filler Treatments

While not quite as lengthy as Sculptra, the injectable filler treatment options listed below also can last long, including:

  • Juvederm (Bellafill Juvederm and some variants)
  • Radiesse
  • Restylane (Restylane Lyft, Restylane Defyne, Restylane Refyne)

These dermal fillers work in the same way that Sculptra does but in slightly different ways.


It is a hyaluronic acid-based facial filler that focuses on the smile and lip lines all around the mouth and nose. It also comes in various types, with Juvederm Voluma (a cheek filler) that lasts until two years. 

Another possible explanation why hyaluronic acid fillers like Juvederm perform so well is the natural collagen regrowth combined with fillers that deliver more supple, more elastic, and fairer skin. With proper amounts, hyaluronic acid-containing products can even benefit in the management of conditions such as eczema.  


Radiesse, like Juvederm and Restylane, increases the level of the collagen manufacturing process of the skin. It accomplishes this by injecting calcium hydroxyapatite into the system, which acts as a filler material and a catalyst for collagen formation.

Radiesse can have both immediate and long-term effects. As the first calcium hydroxyapatite gel is implanted beneath the filler regions, the physical form of the filler locations offers the volume required to fill them in. As the gels disintegrate, the calcium hydroxyapatite is absorbed by the blood system, which aids in rebuilding connective tissue and regenerate lost skin cells.


It is a hyaluronic acid-based facial filler that adds volume to skin folds, iron out wrinkles, and rebuild smooth, supple skin appearance. It is a comparatively quick and painless cosmetic procedure with fewer restrictions for its use on patients.

Restylane is among the most effective product lines in the facial filler market because of its active ingredient. Restylane laso has its Refyne, Defyne, and Lyft varieties, which can help give  more facial volume, more definition, and even both.

Restylane variations can all manage difficult-to-treat areas like tear troughs, nasolabial folds, and marionette lines. They are quick, painless, and have moderate to no adverse effects after the process.

Based on the person’s lifestyle and the treatment area, these three dermal fillers can last from a year or two.

Tips to Prolong the Effects of Dermal Fillers

While there is no miracle way of making the fillers last forever, a few factors are causing the body to absorb the filler faster, reducing the results. By preventing these things, it can keep the dermal filler in excellent condition for a prolonged period.

Eat healthy foods

Everyone enjoys a treat once in a while, but overeating unhealthy food can lead to inflammation. As a result, the dermal fillers may break down quicker. Generally speaking, it is essential to keep the skin firm and healthy to keep the lips looking amazing – this includes plenty of fruits and vegetables and healthy oils and fats in nuts and fish.

Reduce the stress

Stress can harm health in numerous ways, which individuals may not have regarded its impact on lip injections. When people are stressed, the body releases more hormones, which causes filler to tear down faster, shrinking the lip pout sooner. Furthermore, people can’t avoid the entirety of life’s stresses, but experimenting with different stress management techniques may truly help maintain calmness (also lip volume).

Follow the specialist’s aftercare advice

Since lip fillers are an instant treatment with little to no downtime, it may be enticing to immediately resume the daily activities. Moreover, the specialist will provide particular aftercare instructions after the injections, and individuals must follow them.

Avoid excessive sun exposure

It’s advisable to wear SPF every day (even in cloudy weather) and restrict sun exposure between 11 and 3 pm. Not only is this beneficial to the body and skin, but this may also help the lip fillers last longer. Overexposure to UV rays can induce specific kinds of fillers to deteriorate faster.

Learn More: Best Dermal Filler for Areas of Skin Scarring

Get the Ultimate Sculptra Experience at aNu Aesthetics 

woman receiving an injection of dermal fillers in her face

If you want to turn back time and enjoy a fuller, younger look, the team at aNu Aesthetics is always ready to help you. You’ll never have to worry about looking fake or strange with our Sculptra treatment and our team of experts to help you achieve your dream look.

To book a consultation, you may contact our office and pick a suitable schedule. Rest assured that your medical history, underlying diseases, types of medication you are currently undergoing, and beauty goals will all be taken into account. All possible treatment options will be presented and you will be guided every step of the way. Try Sculptra today at aNu Aesthetics.

The Perfect Filler For The Perfect You

What is your perfect cosmetic filler? Whether in your lips, cheeks, or anywhere else, our providers know exactly how to make you look your best. Call us today to learn more.


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